Robert Rucker, Ph.D.

Robert Rucker

Position Title
Distinguished Professor Emeritus
Distinguished Professor Emeritus, Department of Internal Medicine

3415 Meyer Hall
  • M.S. and Ph.D., Biochemistry, Purdue University
Research Interests

Dr. Rucker's current research focus is on the role of nutrients in early growth and development, the physiological roles of quinone cofactors derived from tyrosine, such as pyrroloquinoline quinone, and allometric scaling relevant to nutrition.

Selected past honors and activities:

Past President, American Society for Nutrition; Fellow, American Association for the Advancement of Science; also, American Society for Nutrition; Chair or Co-Chairperson for FASEB Summer Conferences on Micronutrients; service on Program Committees for ASN and FASEB, (e.g. planning committees for Experimental Biology meetings); Plenary Speaker at International Nutrition Congresses; service on the Executive Committees for ASN, Exp. Biol. Med. And committees for USDA, NIH and FASEB; Editorial Board service: American Journal of Clinical Nutrition, Journal of Nutrition, Exp. Biol. Med., Nutrition Research, Annual Reviews of Nutrition; recipient: UC Davis Medical School Oettinger Research Award, American Society for Nutritional Sciences – Bordon Research Award, Distinguished Professor Title at UC Davis (2005). He has also served as Chair and Vice-Chair of the Nutrition Department or in various positions for the Graduate Group for Nutritional Sciences. His research program remains active; however, he is no longer directing new students.

Select Publications – Past 10 Years:

W Chowanadisai, MD Hart, M Strong, DM Graham, RB Rucker, BL Smith, CL Keen. Genetic and Genomic Advances in Developmental Models: Applications for Nutrition Research. Adv Nutr. (2020) Mar 5;nmaa022.doi: 10.1093/advances/nmaa022. Online ahead of print.

K Jonscher and RB Rucker. Pyrroloquinoline quinone: its profile. Effects on the liver and implications for health and disease prevention. In: Dietary Interventions in Liver Disease, eds. R Watson and V Preedy (Cambridge, MA; Academic Press, 2019): 157-68.

RB Rucker, BA Watkins. Inadequate diet descriptions: a conundrum for animal model research. Nutrition Research 65 (2019):1-3.

RB Rucker. Allometric scaling: theory and applications. Functional Foods in Health and Disease 7 (2017): 303-13.

RB Rucker, MR Rucker. Nutrition: ethical issues and challenges. Nutrition Research 36 (2016):1183-1192.

RB Rucker. Pantothenic acid. In: Encyclopedia of Food and Health, vol. 4, eds. B Caballero, P Finglas, and F Toldrá (Oxford, UK: Academic Press, 2016): 205-08.

RB Rucker and W Chowanadisai. Coenzymes and cofactors. In: Encyclopedia of Food and Health, vol. 2, eds. B Caballero, P Finglas, and F Toldrá (Oxford, UK: Academic Press, 2016): 206-24.

RB Rucker, AJ Fascetti, and J Larsen. Vitamins, selected diet-derived factors and minerals. In: Loeb and Quimby’s Clinical Chemistry of Laboratory Animals, 3d ed., eds. D Kurtz, J Prescot, and G Travlos (New York: Taylor and Francis, New York, New York, 2016): 1007-1093.

RB Rucker. Reactive oxygen species: regulation and essential functions. In: Antioxidants in Health and Disease, eds. A Zampelas and E Micha (New York: CRC Press, 2015): 3-22.

J Zhang, S Meruvu, YS Bedi, J Chau, A Arguelles, R Rucker, and M Choudhury. Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. Nutrition Research 35 (2015): 844-49.

RB Rucker, CL Keen, and FM Steinberg. Vitamins and food-derived biofactors. In: Encyclopedia of Agriculture and Food Systems, vol. 5, ed. NK Van Alfen (San Diego, CA: Academic Press, 2014): 356-77.

R Rucker and K Brauerly. Pantothenic acid. In: Handbook of Vitamins, 5th ed., eds. J Zempleni, J Suttie, JF Gregory III, PJ (Boca Raton, FL: CRC Press, 2013): 325-49.

RB Rucker and F Steinberg. Vitamin C. Encyclopedia of Biological Chemistry, 2d ed., eds. W Lennarz, MD Lane (San Diego, CA: Academic Press, 2013): 530-34.

Johnson C, Steinberg F, Rucker, RB. Ascorbic acid. In: Handbook of Vitamins, 5th ed., eds. J Zempleni, J Suttie, JF Gregory III, PJ (Boca Raton, FL: CRC Press, 2013): 515-49.

W Chowanadisai, DM Graham, CL Keen, RB Rucker, and MA Messerli. Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12). Proceedings of the National Academy of Sciences of the United States of America 110 (2013): 9903-08.

W Chowanadisai, DM Graham, CL Keen, RB Rucker, and MA Messerli. A zinc transporter gene required for development of the nervous system. Communicative & Integrative Biology 6 (2013): e26207.

CB Harris, W Chowanadisai, DO Mishchuk, MA Satre, CM Slupsky, and RB Rucker. Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects. Journal of Nutritional Biochemistry 24 (2013): 2076-84.

JW Miller and RB Rucker. Pantothenic acid. In: Present Knowledge in Nutrition, eds. JW Erdman, IA MacDonald, and RM Russell (Washington, DC: ILSI Press, 2012): 375-90

W Chowanadisai, SF Shenoy, E Sharman, CL Keen, JK Liu, and RB Rucker. Well- functioning cell mitochondria promote good health. California Agriculture 65 (2011): 136- 40.

SF Shenoy, W Chowanadisai, E Sharman, CL Keen, JK Liu, and RB Rucker. Biofactors in food promote health by enhancing mitochondrial function. California Agriculture 2011; 65 (2011): 141-47.

K Bauerly, C Harris, W Chowanadisai, J Graham, P Havel, E Tchaparian, M Satre, J Karliner, and RB Rucker. Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. PLoS One 6 (2011): e21779.

W Chowanadisai, KA Bauerly, E Tchaparian, A Wong, GA Cortopassi, and RB Rucker. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. Journal of Biological Chemistry 285 (2010):142-52.

E Tchaparian, L Marshal, G Cutler, K Bauerly, W Chowanadisai, M Satre, C Harris, and RB Rucker. Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways. Biochemistry Journal 429 (2010): 515-26.

In press or in Preparation:

Miller, J.W., Rucker R.B., Rogers L.  Pantothenic Acid. In: Present Knowledge in Nutrition (Update of a chapter published in 2012, cf. ref. 230) ILSI Press, Wash. D.C.

RB Rucker, Starcher BL. Boyd L O'Dell, Ph.D. (1916 - 2019). J Nutr (in press)