Dr. Clifford's research concerned the dynamic and kinetic behavior of nutrient metabolism as it occurs in vivo in humans. Nutrients of special interest include folate, vitamin E, β-carotene, lutein, and food (fruits/vegetables) components (flavonoids, isothiocyanates, catechins, sulfaraphanes, resveratrol). Foods rich in the above components protect against and hold promise for improved management of developmental, chronic, and degenerative diseases.